Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; such as DTL/CDT2; BCL6 and PRDM1/BLIMP1. The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6; thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells. The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL; an important step for the regulation of TGF- beta signaling; cell migration and the timing of the cell-cycle progression and exit. Binds to and neddylates phosphorylated p53/TP53; inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53. {ECO:0000269|PubMed:17098746; ECO:0000269|PubMed:22113614; ECO:0000269|PubMed:23478441; ECO:0000269|PubMed:23478445; ECO:0000269|PubMed:23892434; ECO:0000269|PubMed:24613396}.