May play a role during embryogenesis. May modulate tooth organogenesis since alterations of this protein function affect tooth organs size as well as individual cell fate and survival. In embryonic cells; blockage of the function results in increased number of apoptotic cells; reduced proliferation; alterations in cell shape and fibronection matrix synthesis. {ECO:0000269|PubMed:10415329; ECO:0000269|PubMed:11992732; ECO:0000269|PubMed:12153613}.