Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment. Acts as a PCNA loader; loading PCNA onto primed templates. An RFC-like complex (ctf18- RFC) is formed where ctf18 replaces rfc1 in the RFC complex along with the association of dcc1 and ctf8. This complex is required for efficient establishment of chromosome cohesion during S-phase. {ECO:0000269|PubMed:15226378; ECO:0000269|PubMed:16040599}.